Chip vs Chip

CC2652R vs BlueNRG-LP

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Side-by-side comparison of CC2652R and BlueNRG-LP BLE SoCs.

    
    

      
    

  


  
  
  

    
      

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CC2652R

      

      

    
    
      

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BlueNRG-LP

      

      

    
  

  

  
  

  






  
  

    
CC2652R vs BlueNRG-LP: Multi-Protocol Powerhouse vs. Ultra-Low-Power BLE Specialist


ST's BlueNRG-LP and TI's CC2652R are both ARM-based BLE SoCs, but they are optimized for different application classes. The CC2652R prioritizes protocol flexibility and computational headroom; the BlueNRG-LP pushes the boundaries of BLE power efficiency for healthcare and industrial sensors.




Overview


CC2652R from Texas Instruments is a dual-core multi-protocol SoC combining a 48 MHz Cortex-M4F (application) and Cortex-M0 (radio), supporting BLE 5.1, Thread, Zigbee, and proprietary 2.4 GHz. With 352 KB flash and 352 KB SRAM, it handles complex multi-stack applications with ease. Its Matter/Thread certification and robust TI ecosystem make it a staple of smart home infrastructure development.


BlueNRG-LP (Low Power) from STMicroelectronics is built around a 64 MHz Cortex-M0+ core with 256 KB flash and 64 KB SRAM, packaged in a compact 5 × 5 mm QFN-32 or tiny 2.7 × 2.7 mm WLCSP-34. Critically, it implements BLE 5.2's full feature set including LE Power Control and LE LC3 codec and Auracast." data-category="LE Audio">LE Audio">Isochronous Channels (ISO, the foundation for LE Audio). Its radio achieves a receive current of just 4.6 mA and a deep sleep current of 0.9 µA with the 32 kHz oscillator running — among the best figures in the mainstream BLE market. The BlueNRG-LP targets healthcare monitoring, industrial wireless sensors, and consumer devices where sub-µA sleep and BLE 5.2 feature completeness are required.




Key Differences


    

  • Protocol scope: CC2652R supports BLE + Thread + Zigbee + proprietary; BlueNRG-LP is BLE 5.2-only.
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  • BLE version: BlueNRG-LP implements BLE 5.2 with LE Isochronous Channels (LE Audio prerequisite); CC2652R implements BLE 5.1.
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  • Core: CC2652R uses M4F at 48 MHz with FPU + DSP; BlueNRG-LP uses M0+ at 64 MHz — simpler core but higher clock rate.
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  • RAM: CC2652R has 352 KB vs. BlueNRG-LP's 64 KB — CC2652R has far more working memory.
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  • Sleep current: BlueNRG-LP achieves 0.9 µA deep sleep with RTC; CC2652R achieves ~1 µA — both excellent, BlueNRG-LP marginally better.
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  • Package: BlueNRG-LP available in 2.7 × 2.7 mm WLCSP; CC2652R is 7 × 7 mm QFN only.
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  • LE Audio: BlueNRG-LP supports LE Isochronous Channels enabling future LE Audio (LC3 codec); CC2652R does not.
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  • Healthcare certifications: BlueNRG-LP with STs certified BLE stack has FCC/IC/CE pre-certification; CC2652R similarly certified through TI's launchpad reference designs.
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Use Cases


CC2652R Excels At


Multi-protocol smart home devices — the CC2652R's ability to run Thread and BLE simultaneously while maintaining a Zigbee network is a capability BlueNRG-LP cannot replicate. Any product participating in the Matter ecosystem via Thread belongs on the CC2652R.


Data-intensive BLE applications with local processing — waveform analysis, on-device sensor fusion, or running multiple concurrent BLE connections — need CC2652R's 352 KB SRAM to hold all the necessary buffers and application state.


BlueNRG-LP Excels At


Wearable medical sensors — continuous blood pressure cuffs, glucose monitors, and multi-lead ECG patches — benefit from BlueNRG-LP's combination of ultra-low sleep current, compact 2.7 mm WLCSP packaging, and certified BLE 5.2 stack. These devices spend 99% of their time sleeping and transmit small, infrequent data bursts.


Industrial wireless sensors deployed in remote locations on primary lithium cells (AA, 3.6 V LS14500) can achieve 5–10 year lifetimes using BlueNRG-LP's 0.9 µA sleep profile, which CC2652R cannot quite match.


LE Audio accessories — future hearables, hearing aids, and broadcast audio receivers — require LE Isochronous Channels support, which BlueNRG-LP provides and CC2652R does not.




Verdict


The CC2652R is the correct platform when multi-protocol versatility, large RAM, or Matter/Thread participation is required. It is a mature, proven SoC for smart home infrastructure.


The BlueNRG-LP wins when BLE 5.2 compliance (including LE Audio foundations), ultra-low sleep current, miniaturized packaging, or healthcare sensor form factors are the design drivers. Its 0.9 µA deep sleep and 2.7 mm WLCSP packaging enable product designs that the CC2652R's larger footprint and protocol focus cannot easily accommodate.

  

  

  
  

  
  

    




  
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Our comparisons use verified datasheet specifications to create side-by-side tables. Each comparison includes a verdict explaining when to choose each option based on your project requirements.